Cepton Medicated Skin Wash contains 1% chlorhexidine.

Dermalex Rosacea reduces the typical symptoms of rosacea by promoting the full restoration of the skin’s barrier function. It also protects the skin through special UV filters neutralising an important trigger in the appearance of rosacea and couperose symptoms. It restores the skin barrier, treating the rosacea symptoms, and fortifies the skin barrier, protecting from new flare-ups.

A humanised immunoglobulin G1 (IgG1) monoclonal antibody that selectively binds with high affinity to the p19 subunit of human interleukin 23 (IL-23) cytokine without binding to IL-12 and inhibits its interaction with the IL-23 receptor complex. IL-23 is a cytokine that is involved in inflammatory and immune responses. By blocking IL-23 from binding to its receptor, risankizumab inhibits IL-23-dependent cell signalling and release of proinflammatory cytokines.

Immunosuppressant tumour necrosis factor alpha (TNF-a) inhibitor that binds specifically to TNF and neutralises the biological function of TNF by blocking its interaction with the p55 and p75 cell surface TNF receptors. It also modulates biological responses that are induced or regulated by TNF, including changes in the levels of adhesion molecules responsible for leukocyte migration (ELAM-1, VCAM-1, and ICAM-1 with an IC50 of 0.1-0.2 nM).

Rinvoq (upadacitinib) is a selective and reversible Janus kinase (JAK) inhibitor. JAKs are intracellular enzymes that transmit cytokine or growth factor signals involved in a broad range of cellular processes including inflammatory responses, hematopoiesis, and immune surveillance. The JAK family of enzymes contains four members, JAK1, JAK2, JAK3 and TYK2 which work in pairs to phosphorylate and activate signal transducers and activators of transcription (STATs). This phosphorylation, in turn, modulates gene expression and cellular function. JAK1 is important in inflammatory cytokine signals while JAK2 is important for red blood cell maturation and JAK3 signals play a role in immune surveillance and lymphocyte function.

Shampoo containing the active antifungal ketoconazole 2% that works by destroying malassezia and other fungi.

Ritlecitinib irreversibly and selectively inhibitsjanus kinase (JAK) 3 and the tyrosine kinase expressed in hepatocellular carcinoma (TEC) kinase family by blocking the adenosine triphosphate (ATP) binding site. In cellular settings, ritlecitinib specifically inhibits γ -common cytokines (IL-2, IL-4, IL-7, IL-15 and IL-21) signalling through JAK3-dependent common-γ chain receptors.

Biosimilar of infliximab (Remicade).

Enbrel (etanercept) is a fully human soluble TNF receptor fusion protein. TNF is a dominant cytokine in the inflammatory process of rheumatoid arthritis. Elevated levels of TNF are also found in the synovium and psoriatic plaques of patients with psoriatic arthritis and in serum and synovial tissue of patients with ankylosing spondylitis. In plaque psoriasis, infiltration by inflammatory cells, including T-cells, leads to increased TNF levels in psoriatic lesions compared with levels in uninvolved skin. Etanercept is a soluble TNF receptor that is a competitive inhibitor of TNF binding to its cell surface receptor, thereby inhibiting biological activity of TNF. This product entry refers to Enbrel, not biosimilars of etanercept

Tioconazole is an imidazole that is active against commonly occurring dermatophyte and yeast-like fungal species. It is fungicidal in murine models vs Candida spp., T. rubrum and T. mentacrophytes. In vitro, it is fungicidal to pathenogenic dermatophytes, yeasts and other fungi