Dermatology Handbook
For UK audiences

The professionals guide to product selection

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Diflucan
Pfizer

Diflucan

Diflucan contains fluconazole, a triazole antifungal agent. Its primary mode of action is the inhibition of fungal cytochrome P-450-mediated 14 alpha-lanosterol demethylation, an essential step in fungal ergosterol biosynthesis. The accumulation of 14 alpha-methyl sterols correlates with the subsequent loss of ergosterol in the fungal cell membrane and may be responsible for the antifungal activity of fluconazole. Fluconazole has been shown to be more selective for fungal cytochrome P-450 enzymes than for various mammalian cytochrome P-450 enzyme systems
Abrocitinib (Cibinqo)
Pfizer

Abrocitinib (Cibinqo)

The biologic abrocitinib is a janus kinase (JAK)1 inhibitor. JAKs are intracellular enzymes which transmit signals arising from cytokine or growth factor-receptor interactions on the cellular membrane to influence cellular processes of haematopoiesis and immune cell function. JAKs phosphorylate and activate Signal Transducers and Activators of Transcription (STATs) which modulate intracellular activity including gene expression. Inhibition of JAK1 modulates the signalling pathways by preventing the phosphorylation and activation of STATs.
Dalacin T
Pfizer

Dalacin T

Dalacin T is an anti-infective treatment for acne. The active constituent, clindamycin, is a known antibiotic. When applied topically, it is found in comedone samples at sufficient levels to be active against most strains of Propionibacteria acnes.
Vibramycin-D
Pfizer

Vibramycin-D

Vibramycin is primarily bacteriostatic and is believed to exert its antimicrobial effect by the inhibition of protein synthesis. Vibramycin is active against a wide range of Gram-positive and Gram-negative bacteria and certain other micro-organisms.
Full Marks
Reckitt Benckiser

Full Marks

Full Marks contains isopropyl myristate and cyclomethicone. It is a thin, oily liquid, which spreads quickly and completely through the hair to saturate the scalp and kill head lice and eliminate their eggs. Using the fine-tooth metal comb provided, the solution is then combed through the hair once the required time has elapsed
Derbac–M
Reckitt Benckiser

Derbac–M

Derbac M Liquid contains malathion, a widely used organophosphorus insecticide that inhibits cholinesterase. It is effective against a wide range of insects, but is one of the least toxic organophosphorus insecticides as it is rapidly detoxified by plasma carboxylesterases
E45 Wash Cream
Reckitt Benckiser

E45 Wash Cream

E45 Wash Cream is an emollient soap substitute that is clinically proven to wash dry and itchy skin conditions
E45 Bath Oil
Reckitt Benckiser

E45 Bath Oil

An effective yet gentle bath oil that is clinically proven to soothe and moisturise dry skin. It creates a lasting barrier that protects against moisture loss
Isotretinoin (RoAccutane)
Neon Healthcare

Isotretinoin (RoAccutane)

Retinoid. Isotretinoin is a stereoisomer of all-trans retinoic acid (tretinoin). The exact mechanism of action of isotretinoin has not yet been elucidated in detail, but it has been established that the improvement observed in the clinical picture of severe acne is associated with suppression of sebaceous gland activity and a histologically demonstrated reduction in the size of the sebaceous glands. Furthermore, a dermal anti-inflammatory effect of isotretinoin has been established
Pro-Banthine
Kyowa Kirin

Pro-Banthine

Tablets containing 15mg of the antispasmodic propantheline bromide