Dermatology Handbook
For UK audiences

The professionals guide to product selection

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Derbac–M
Reckitt Benckiser

Derbac–M

Derbac M Liquid contains malathion, a widely used organophosphorus insecticide that inhibits cholinesterase. It is effective against a wide range of insects, but is one of the least toxic organophosphorus insecticides as it is rapidly detoxified by plasma carboxylesterases
E45 Wash Cream
Reckitt Benckiser

E45 Wash Cream

E45 Wash Cream is an emollient soap substitute that is clinically proven to wash dry and itchy skin conditions
E45 Bath Oil
Reckitt Benckiser

E45 Bath Oil

An effective yet gentle bath oil that is clinically proven to soothe and moisturise dry skin. It creates a lasting barrier that protects against moisture loss
Isotretinoin (RoAccutane)
Neon Healthcare

Isotretinoin (RoAccutane)

Retinoid. Isotretinoin is a stereoisomer of all-trans retinoic acid (tretinoin). The exact mechanism of action of isotretinoin has not yet been elucidated in detail, but it has been established that the improvement observed in the clinical picture of severe acne is associated with suppression of sebaceous gland activity and a histologically demonstrated reduction in the size of the sebaceous glands. Furthermore, a dermal anti-inflammatory effect of isotretinoin has been established
Pro-Banthine
Kyowa Kirin

Pro-Banthine

Tablets containing 15mg of the antispasmodic propantheline bromide
Footmender All In One Foot Cream
Footmender

Footmender All In One Foot Cream

Footmender All In One Foot Cream has eight active ingredients that create the following effects: antimicrobial effect that prevents the regrowth of microorganisms for at least 12 hours; an exfoliating effect that removes dead skin cells; footmender binds and retains moisture in the skin; softens the skin; reduces skin sensitivity and slows the release of water; stabilises skin cell renewal; stimulates the healing of cracked skin and strengthens the skin’s barrier effect
Enstilar Cutaneous Foam
LEO Pharma

Enstilar Cutaneous Foam

The active ingredients in Enstilar Cutaneous Foam are calcipotriol (as monohydrate) and betamethasone (as dipropionate). Enstilar contains a combination of calcipotriol and betamethasone dipropionate. Calcipotriol is a vitamin D analogue. In vitro data suggest that calcipotriol induces differentiation and suppresses proliferation of keratinocytes. This is the proposed basis for its effect in psoriasis. Betamethasone dipropionate is a potent topical corticosteroid with anti-inflammatory, antipruritic, vasoconstrictive and immunosuppressive properties, although it does not cure the underlying condition.
Dovobet Ointment
LEO Pharma

Dovobet Ointment

Calcipotriol is a vitamin D derivative. In vitro data suggest that it induces differentiation and suppresses proliferation of keratinocytes. This is the proposed basis for its effect in psoriasis
Dovobet Gel
LEO Pharma

Dovobet Gel

Contains calcipotriol and betamethasone. Calcipotriol helps to bring the rate of skin cell growth back to normal and betamethasone acts to reduce inflammation.
Brodalumab (Kyntheum)
LEO Pharma

Brodalumab (Kyntheum)

Brodalumab is a recombinant fully human monoclonal immunoglobulin IgG2 antibody that binds with high affinity to human IL-17RA and blocks the biological activities of the pro-inflammatory cytokines IL-17A, IL-17F, IL-17A/F heterodimer and IL-25, resulting in inhibition of the inflammation and clinical symptoms associated with psoriasis. IL-17RA is a protein expressed on the cell surface and is a required component of receptor complexes used by multiple IL-17 family cytokines. IL-17 family cytokine concentrations have been reported to be increased in psoriasis. Blocking IL-17RA inhibits IL-17 cytokine-induced responses resulting in normalisation of inflammation in the skin.