Implantable grade calcium sulfate matrix with aqueous mixing solution, supplied in pre-measured quantities. The calcium matrix is composed of >98% calcium sulfate (calcium sulfate hemihydrate with ≤2% calcium sulfate dihydrate) and ≤2% inorganic additives. When mixed, the resultant paste may be implanted into open voids/gaps of the musculoskeletal system to set in situ or placed in the bead mould mat provided to form beads for implantation. The biodegradable, radiopaque beads are absorbed by the body in approximately 30–60 days. Accessories are provided for preparation and use. Product, accessories and packaging are not made from natural rubber latex. Non-metallic and non-magnetic and poses no known hazards in all magnetic resonance environments. Suitable as a carrier material for substances such as antibiotics. Intended to be gently packed into bony voids or gaps of the skeletal system (i.e. extremities, pelvis, and posterolateral spine). It absorbs and is replaced with bone during the healing process. Biodegradable and biocompatible.